The Lab

Laboratory-Grade Everything.
No Exceptions.

Every instrument we use, every method we run, and every result we issue is documented, validated, and traceable. You don't have to trust us — you can verify every claim we make about our analytical capabilities.

Our Instrumentation

All instruments are calibrated on a defined schedule with traceable standards. Calibration records and system suitability data are documented on every COA.

Shimadzu Prominence HPLC

LC-20AD

HPLC-UV Purity Analysis

  • Dual-pump gradient system
  • Diode array detector (DAD)
  • Column thermostat ± 0.1°C
  • Autosampler with 105-vial capacity
  • Kinetex C18 column, 150×4.6mm, 5µm
USP <621> / ICH Q2(R1)

Waters ACQUITY UPLC-TQ-S

ACQUITY UPLC H-Class

LC-MS/MS Identity Confirmation

  • Ultra-high performance LC system
  • Triple quadrupole mass spectrometer
  • ESI+ and ESI- ionization
  • 200–3000 m/z mass range
  • Sub-picomole detection sensitivity
ICH Q6B / USP <1058>

Agilent 7900 ICP-MS

Series 7900

Heavy Metal Screening

  • OctopoleReaction System (ORS)
  • High-matrix introduction (HMI)
  • Sub-ppb detection limits
  • 8-element simultaneous screening
  • Rh/Ge internal standard correction
USP <232> / USP <233>

Agilent 7890B GC-FID

7890B with headspace sampler

Residual Solvents Analysis

  • Headspace sampling — 60 vial carousel
  • Flame ionization detection
  • Dual column capability (DB-624 / DB-5)
  • ICH Q3C Class 1, 2, and 3 panels
  • ± 1% quantitative accuracy
USP <467> / ICH Q3C

Endosafe® LAL Kinetic System

Charles River Endosafe nexgen-PTS

Endotoxin Testing

  • Kinetic turbidimetric LAL method
  • 0.005 EU/mL detection limit
  • USP <85> compliant
  • FDA/EMA regulatory-grade assay
  • 30-minute result time
USP <85> / EP 2.6.14

Microbiology Incubators

Thermo Scientific

Microbial Limits Testing

  • 30–35°C aerobic incubation (TAMC)
  • 20–25°C incubation (TYMC)
  • HEPA-filtered laminar flow hood
  • Soybean Casein Digest agar (SCDA)
  • Sabouraud Dextrose agar (SDA)
USP <61> / USP <62>

Compliance & Method Standards

All Aegis methods are validated against international reference standards and regulatory guidance. Testing is not performed to internal standards — it is performed to published, auditable ones.

USP <621>

Chromatography

Governing standard for all HPLC-UV purity methodology, system suitability, and calibration.

USP <731>

Loss on Drying

Moisture content determination for hygroscopic peptide powders on request.

USP <232>

Elemental Impurities Limits

Oral and parenteral elemental impurity acceptance limits used for ICP-MS pass/fail criteria.

USP <233>

Elemental Impurities Procedures

Sample preparation and quantitation procedures for ICP-MS heavy metal analysis.

USP <61>

Microbial Examination (Non-Sterile)

Standardized method for total aerobic microbial count (TAMC) determination.

USP <62>

Microbial Examination (Specified Organisms)

Yeast and mold count (TYMC) and specified organism screening methodology.

USP <85>

Bacterial Endotoxins Test

Kinetic LAL turbidimetric endotoxin assay per current USP chapter.

USP <467>

Residual Solvents

GC headspace method for detection and quantification of ICH Q3C solvents.

ICH Q2(R1)

Validation of Analytical Procedures

Framework for method validation including accuracy, precision, linearity, and LOQ/LOD.

ICH Q3C

Impurities: Residual Solvents

Guidance for classification and limits of residual solvents in pharmaceutical products.

ICH Q6B

Specifications: Biotechnological Products

Applied to LC-MS/MS identity confirmation methodology for complex peptides.

FDA Guidance

Elemental Impurities (2018)

Regulatory guidance harmonized with USP <232>/<233> for elemental impurity control.

Chain of Custody

Every sample has a documented chain of custody from receipt through COA issuance. Nothing is assumed. Everything is recorded.

1

Sample Receipt

Unique Sample ID assigned. Sample weighed, logged, photographed, and entered into LIMS within 2 hours of receipt.

2

Sample Prep

Preparation documented with analyst ID, date, diluent lot numbers, and reference standard lot/expiry. Witnessed where required.

3

Instrument Run

Run sequence, instrument ID, column lot, calibration ID, and system suitability results recorded in LIMS.

4

Data Review

Raw data reviewed by a second analyst for integration, acceptance criteria, and calculation accuracy before approval.

5

QC Sign-off

Lab director reviews and digitally signs off on the COA before issuance. Any out-of-specification results trigger investigation.

6

COA Issuance

Certificate issued, write-protected, and simultaneously published to public verification database. PDF sent to client.

Quality Metrics

99.7%

Measurement Accuracy

< 2%

Intra-day CV (HPLC)

0.05%

LOQ — Relative Purity

Sub-ppb

Heavy Metal Detection

Ready to Put Our Lab to Work?

Every instrument described on this page will be involved in testing your sample. No outsourcing. No contract labs. Results you can trust.